Dr. Kalamegam Gauthaman is an Associate Professor at the ‘Center of Excellence in Genomic Medicine Research, King Abdulaziz University. He graduated as a doctor (MBBS, India) and later received his doctoral degree from the National University of Singapore (PhD, Singapore).
His research expertise covers (i) the use of human embryonic stem cell (hESC) as a pharmaceutical screening tool for the study of potential drugs, their expansion in 2D/3D environments, their prolonged preservation, elimination of tumorigeneic (teratoma) potential; (ii) the derivation of human Mesenchymal stem cells (MSCs) from various sources (umbilical cord, bone-marrow, synovial tissue, dental pulp), their differentiation into useful tissues for the management of osteoarthritis, chronic non-healing skin ulcers, Alzheimer’s disease; (iii) evaluation of their anti-tumorigenic properties of stem cells against human primary cancers and cancer cell lines; and (iv) screening of phytochemicals (natural products) using physio-pharmacological assays on human tissue. He has won national and international competitive grants in the past and has successfully completed them. He has guided and trained 10 MSc and 3 PhD scholars leading to their award of respective degrees. To his credit he holds 01 patent (USA), 03 provisional patents (USA) and has published more than 60 research / review articles in peer reviewed scientific journals. He has also contributed to 07 book chapters and several international conference presentations.
The state-of-the-art tissue culture/stem cell facility at CEGMR is routinely involved in performing several in vitro assays (morphological, proliferation, cell cycle, cell death, protein expression, gene expression) related to physio-pharmacology, molecular biology, stem cell biology, cancer biology, nanotechnology and tissue engineering.