The Power through Knowledge is a famous slogan signifying deep sincere efforts of COMS to achieve excellence in many of ours genomic medicine diagnostic and research services aimed primarily at making the humanity free from genetic diseases. To realize this dream, a service workforce comparable to the best in the world has been created armed with the skills under the umbrella of COMS. This is why the COMS gets its birth. COMS lays emphasis on all sorts of services dealing with cytogenetic, molecular, biotechnological and diagnostics. Dealing in major research projects is another active area. Accreditation, training programs and educational research is pursued to disseminate knowledge. A separate COMS Publication Division is a significant move to present findings at international level. More important, COMS specializes to provide individual or peer to peer consultations. Some of these services are elaborated in a comprehensive way.